Short-chain fatty acids (SCFAs) produced by gut microbiota may play a role in modulating blood pressure by acting on two major SCFA receptors, olfactory receptor 78 (Olfr78) and Gpr41, a study finds. Jennifer L. Pluznick and colleagues found that Olfr78 was expressed in the kidney and mediates renin secretion in response to SCFAs, particularly propionate.
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