The September 2014 Annual Thematic Issue of Experimental Biology and Medicine is devoted to “The biology and medicine of microphysiological systems.” Papers by participants in the NIH Microphysiological Systems (MPS) Program describe MPS as in vitro models for bone/cartilage, brain, gastrointestinal tract, lung, liver, microvasculature, reproductive tract, skeletal muscle, and skin; the interconnection of MPS to support physiologically based pharmacokinetics and drug discovery and screening; and the microscale technologies that regulate stem cell differentiation.
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