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Genetic mutations identified during remission may help predict risk of relapse, survival for leukemia patients

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In preliminary research, the detection of persistent leukemia-associated genetic mutations in at least 5 percent of bone marrow cells in day 30 remission samples among adult patients with acute myeloid leukemia was associated with an increased risk of relapse and reduced overall survival, according to a study in the Aug. 25 issue of JAMA.

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