Coupling reaction usually refers to the direct C–C bond formation between two carbon fragments. Generally, cross-coupling reactions between nucleophiles and electrophiles have been extensively studied and become the classic model for bond constructions. Another reaction model, bond formation from two nucleophiles through oxidative cross-coupling, has received more and more attention over the past few years. A paper published in 2015(16) issue of Science Bulletin discussed the concept of oxidative cross-coupling and give an overview of its recent development.
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