Flocculation of ternary supramolecular nanoparticle networks (NPN) can be applied for Concanavalin A (ConA) detection: NPN form and flocculate due to the orthogonal binding of bifunctional linker molecules to quantum dots and lectins. Monitoring the decrease in quantum-dot fluorescence intensity over time, caused by controlled network formation and flocculation, allows for selective, qualitative and quantitative lectin detection.
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