Researchers examined the origin, migration pathway, initial settling position, and secondary dispersion of cells from the subplate zone, a transient cellular compartment in the embryonic cerebrum, in macaque embryos, compared the findings to fetal human forebrain tissue, and found that the subplate zone in primates has a more dynamic and complex developmental history than previously understood, findings that may have implications for understanding disorders such as childhood epilepsy, autism, and schizophrenia.
↧