PharmaMar will start a Phase III study of PM1183 in combination with...
The unparalleled results obtained in the Phase Ib study support the start of a head-to-head study in relapsed small-cell lung cancer (SCLC) patients that will compare the combination as second line...
View ArticleCommunity-wide cardiovascular disease prevention programs associated with...
In a rural Maine county, sustained, community-wide programs targeting cardiovascular risk factors and behavior changes were associated with reductions in hospitalization and death rates over a 40 year...
View ArticleUse of surgical procedure to facilitate child birth declines
Between 2006 and 2012 in the U.S., there was a decline in rates of episiotomy, a surgical procedure for widening the outlet of the birth canal to make it easier for the mother to give birth, according...
View ArticlePinning down the harmful mutations that cause heart muscle disease
A study of more than 5,000 people, one of the largest of its kind to date, uncovers the mutations in the giant muscle protein titin that cause dilated cardiomyopathy.
View ArticleOpinions about ability might affect women’s academic participation
The results of a national survey in the United States suggest that the representation of women in academia might reflect peoples’ general attitudes about what it takes to excel in various disciplines....
View ArticleGeese use “roller coaster” strategy to fly over Himalayas
By remotely monitoring bar-headed geese in the Himalayan Mountains, Charles Bishop and colleagues show that the birds hug the terrain as they fly, riding the peaks and valleys like the hills and dips...
View ArticleNew vegetation record syncs with cenozoic climate record
Researchers have developed a way to reconstruct vegetation structure, or the degree of open forest canopy, and they used it to estimate what vegetation might have looked like during the middle...
View ArticleSwelled tissues burst limits of microscope
There are limits to how well a light microscope can magnify the tiny details in a cell or tissue. So why not blow up the biological material itself to a larger size? That’s the solution proposed by...
View ArticleSPECTAcolor viable next generation multinational cancer clinical trial...
SPECTAcolor's successful start has demonstrated its viability to facilitate next generation cancer clinical trials. It has been successfully implemented across 19 clinical centers located in nine...
View ArticleOptic fiber for recording the temperature in extreme industrial environments
Optic fiber is normally used in the field of telecommunications to transmit information using light, but a group of researchers at the Universidad Carlos III de Madrid (UC3M) has developed a technique...
View ArticleAlso of interest from the Proceedings of the National Academy of Sciences
A study of more than 5,000 Himalayan mountain climbing expeditions involving climbers from 56 countries finds that expeditions from countries with hierarchical cultures had more climbers reaching the...
View ArticleMetrics of film significance
An analysis of networks of citations among more than 15,000 films listed in the Internet Movie Database may produce several automated metrics of a film’s significance, according to a study. Judgments...
View ArticleCalifornia’s changing forests
A study of forest vegetation trends in California finds a decrease in large trees, an increase in forest density, and an increased abundance of oaks relative to pines, indicating changes associated...
View ArticleCanine distemper and Serengeti lions
A study in Tanzania suggests that domestic dogs may have spread canine distemper virus (CDV) to Serengeti lions but that subsequent infection peaks may have been caused by other carnivore species. CDV...
View ArticleDeforestation and greenhouse gas emissions reductions in Indonesia
A recent moratorium on deforestation activities in Indonesia has reduced greenhouse gas emissions but not to a level sufficient to reach current targets, according to a study. In May 2011, Indonesia...
View ArticleArid air and language tonality
Climatic conditions such as temperature and humidity that affect the performance of the vocal folds may constrain development of complex tones in language to warm, humid regions, according to a study....
View ArticleVenomous cone snails may use insulin to net prey
Some predatory cone snails might use insulin contained in their venom to induce low blood sugar in schools of swimming fish, slowing down and netting prey through metabolic manipulation, according to...
View ArticleNew hope for understanding sudden cardiac arrest
New biosciences research at the University of Kent could point the way to greater understanding of the heart mutations that cause sudden cardiac arrest.
View ArticleHospitalization for pneumonia associated with increased risk of...
Hospitalization with pneumonia in older adults was associated with an increased short-term and long-term risk of cardiovascular disease (CVD), suggesting that pneumonia may be an important risk factor...
View ArticleWorking collaboratively may help reduce medical errors
Medical students who worked in pairs were more accurate in diagnosing simulated patient cases compared to students who worked alone, according to a study in the January 20 issue of JAMA.
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