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Gene expression profiles of single brain cells

Researchers report a method for classifying individual cells in the human brain based on gene expression profiles. The human brain contains an enormous variety of cell types that differ in gene...

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Disease forecasting through machine learning

Researchers report a method for predicting new sources of rodent-borne diseases. As animal-borne disease outbreaks increase in frequency, anticipating future outbreaks becomes a public health priority.

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Mobility, agriculture, and bone strength

Changes to human bone strength during the Holocene Epoch may be due to dramatic changes in mobility following the initiation of agriculture, according to a study. Declining bone strength relative to...

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Also of interest from the Proceedings of the National Academy of Sciences

Researchers report that mice expressing a defective form of an enzyme that cleaves chitin, a major component of dust mite exoskeletons, exhibited increased inflammatory responses to inhaled dust mites...

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Where the Rubber Meets the Road

Researchers combine simple experiments first employed by Leonardo da Vinci with advanced theory to reveal new atomic-level insights into what happens when rubber slides across asphalt.

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Photonic Crystal Nanolaser Biosensor Simplifies DNA Detection

As the team of Yokohama National University researchers in Japan reports in Applied Physics Letters, from AIP Publishing, they created a photonic crystal nanolaser biosensor capable of detecting the...

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Harvesting Energy from Electromagnetic Waves

This week in the journal Applied Physics Letters, from AIP Publishing, researchers from the University of Waterloo in Canada report a novel design for electromagnetic energy harvesting based on the...

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Studies examine prevalence of amyloid among adults and its association with...

Two studies in the May 19 issue of JAMA analyze the prevalence of the plaque amyloid among adults of varying ages, with and without dementia, and its association with cognitive impairment.

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Secrets of an ancient Chinese remedy for malaria finally uncovered

An ancient Chinese herbal medicine for malaria, known scientifically as febrifugine, works by disrupting the parasites’ protein-building machinery, a new study shows. A compound based on febrifugine...

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Overlooked protein drives tissue fibrosis

A new study uncovers an overlooked protein’s role in driving fibrosis, or excessive scarring of tissue. Blocking this protein, known as αvβ1 integrin, reduced fibrotic tissue in mice, offering a new...

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China Century signs agreement with University of Chicago Medicine

China Century Group and the University of Chicago Medicine signed an exclusive agreement Thursday to improve health care delivery in China by bringing international standards and best practices to...

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Tara Oceans Expedition yields treasure trove of plankton data

In five related reports in this issue of the journal Science, a multinational team of researchers who spent three and a half years sampling the ocean’s sunlit upper layers aboard the schooner Tara...

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Paraplegic patient reveals neurons behind planning

Microelectrodes implanted in the brain of a paraplegic patient are telling researchers more about the neuronal activity underlying our physical movements. These new findings represent an important...

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Similarities seen between cancerous and sun-Exposed cells

Normal human skin cells harbor a surprisingly large number of acquired mutations, including many known cancer-promoters that are under strong positive selection, researchers say. These new findings...

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Inland ice in Antarctica melting fast

Many glaciers on the Southern Antarctic Peninsula (SAP) became destabilized in 2009 and have melted at accelerating rates since then, researchers say. These glaciers, which rest on bedrock that dips...

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Tunable liquid metal antennas

Using electrochemistry, North Carolina State University researchers have created a reconfigurable, voltage-controlled liquid metal antenna that may play a huge role in future mobile devices and the...

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Subclinical hyperthyroidism associated with an increased risk of hip and...

In an analysis that included more than 70,000 participants from 13 studies, subclinical hyperthyroidism was associated with an increased risk for hip and other fractures including spine, according to...

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Soy isoflavone supplement does not improve symptoms, lung function for...

Although some data have suggested that supplementation with soy isoflavone may be an effective treatment for patients with poor asthma control, a randomized trial that included nearly 400 children and...

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Oxidation chemistry of biogenic emissions

The structure of biogenic compounds emitted into the atmosphere can affect how the compounds are oxidized, according to a study. Aerosol particles, a major source of cloud condensation nuclei, can...

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Also of interest from the Proceedings of the National Academy of Sciences

To find ovarian tumor-specific molecules that could be used as diagnostic and therapeutic targets, custom bioinformatics algorithms were developed and used to analyze gene expression data from 296...

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