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Research relates another receptor to Alzheimer’s

Researchers have identified a receptor in the mouse brain, known as PirB, which binds to the beta-amyloid peptide (associated with Alzheimer’s disease) and causes neuronal defects. In light of their...

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Opioid dependence plays role in chronic pain

The body’s dependence on natural, pain-blocking opioids after injury may contribute to the emergence of chronic pain, a new study reports. Blocking the body’s overuse of opioids could potentially...

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What made the deepest earthquake so deep?

To help the seismological community better understand just what causes elusive deep earthquakes, scientists have studied the energy released from the largest such event recorded to date.

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Prostacyclin analogs and PDE 5 inhibitors synergistically stimulate ATP...

Prostacyclin (PGI2) and phosphodiesterase 5 (PDE5) inhibitors are vasodilators used in the treatment of pulmonary arterial hypertension (PAH). Although these drugs stimulate vascular dilation directly,...

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A macaque model of Middle Eastern coronavirus infection

Researchers have created an animal model of the deadly Middle Eastern respiratory coronavirus infection that may help identify strategies to protect against Middle East Respiratory Syndrome (MERS)....

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Computer simulation helps predict time and place of empires’ origins

Computer simulation can help predict with 65% accuracy where and when the largest-scale complex societies arose in human history, a study demonstrates. To study the origin of empires using historical...

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Naps might help enhance preschool learning

Preschoolers who took mid-day naps were better at retaining material learned in the morning than children who did not nap, according to a study. Recent studies in young adults show that nighttime sleep...

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Parental care may lighten the toll of childhood abuse

A loving, supportive parent may help buffer the long-term health effects of childhood abuse, a study suggests. Verbal or physical abuse during childhood has been linked to a host of health conditions...

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Interpretation of carbon nanotube-caused damage to the respiratory system

With the increasing large-scale production and application of CNTs, their bio-safety assessment has raised wide attention. A recent review has summarized the mechanism underlying CNT-caused pulmonary...

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Reductive immobilization of ReO4- in soil and groundwater using...

Synthetic stabilized ZVI nanoparticles were used to immobilize metallic contamination in situ. The current research discovered this technology has been applied in immobilizing ReO4- in groundwater/soil...

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analysis of differentially expressed genes between Kashin-Beck disease and...

Kashin-Beck disease and Keshan disease are mainly endemic diseases in China. These two diseases have similar etiological hypothesis and endemic area, but the etiology and pathogenesis of the two...

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Subduction channel processes: New progress in plate tectonic theory

How is plate subduction factory operated during continental collision? How do physical mixing and chemical reaction proceed at colliding continental margins of different depths? How is continental...

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Northern moths may fare better under climate warming than expected

Moths in northern Finland are less susceptible to rising temperatures than expected, suggesting high latitude moth populations around the world may be partly buffered from the effects of rapid climate...

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Combining diet and exercise for knee osteoarthritis produces greater...

Among overweight and obese adults with knee osteoarthritis, combining intensive diet and exercise led to less knee pain and better function after 18 months than diet-alone and exercise-alone, according...

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Sensor-augmented insulin pump therapy reduces rate of severe hypoglycemic events

Use of an insulin pump with a sensor that suspends insulin delivery when blood glucose falls below a set threshold reduced the rate of severe and moderate hypoglycemia among patients with type 1...

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A no-needle nanocapsule vaccine

A nanocapsule-based vaccine delivered through mucosal points of entry like the nose may effectively protect against pathogens, reports a new study in mice. Mucosal vaccines are appealing because they...

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Reliable and sustainable comprehensive care for frail elderly people

“The United States needs arrangements that allow elderly people to live with confidence, comfort, and meaningfulness at a cost that families can afford and the nation can sustain …

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Analysis of health care in U.S. indicates that improvement in outcomes has...

An examination of health care in the U.S. finds that despite the extraordinary economic success of many of its participants, the health care system has performed relatively poorly by some measures; and...

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Microbes may aid hyena communication

Microbes in the scent glands of hyenas produce odorous compounds that hyenas use to communicate with one another, a study suggests. Many animals communicate using odorous secretions from scent glands,...

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Transmission of a Parkinson disease variant from humans to mice

A study reports that the aggregates of α-synuclein protein that form in the brain of individuals with the neurodegenerative disorder multiple system atrophy (MSA), a variant of Parkinson disease,...

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