Also of interest from the Proceedings of the National Academy of Sciences
Researchers have generated HIV-resistant immune cells from induced pluripotent stem cells derived from blood mononuclear cells of two donors using a combination of transposon-based and genome editing...
View ArticleFor patients receiving metformin to treat diabetes, addition of insulin...
Among patients with diabetes who were receiving metformin, the addition of insulin compared with a sulfonylurea (a class of antidiabetic drugs) was associated with an increased risk of nonfatal...
View ArticleLong-term follow-up after bariatric surgery shows greater rate of diabetes...
In a study that included long-term follow-up of obese patients with type 2 diabetes, bariatric surgery was associated with more frequent diabetes remission and fewer complications than patients who...
View ArticleLighting up tumors with phospholipid compounds
Radiolabeled, fluorescent phospholipid compounds designed in the lab can detect and track cancer spread, targeting even those cells that have been relatively resistant to current therapies, a new...
View ArticleDinosaurs -- not too fast, not too slow
Dinosaurs’ metabolic rates -- once thought to be slow, leaving these now-extinct animals to lumber across the landscape -- can’t be characterized as slow and ectothermic (reflecting an...
View ArticleFine-tooth comb on Mexico’s genetics for medical purposes
Researchers have pored over the genetics of the people of Mexico, and their fine-scale study -- the first of its kind in the region -- reveals how the genomes of modern Mexicans were shaped by...
View ArticleAnxious crayfish can be treated like humans
A new study in crayfish -- the freshwater crustaceans that look like miniature lobsters -- reveals that these crustaceans experience a primitive form of anxiety, which probably shares some...
View ArticleDo fragmented forests open the door to diseases?
The results of a 12-year field study suggest that highly connected plant populations are more resistant to fungal pathogens than isolated populations. This finding, reported by Jussi Jousimo and...
View ArticleRescue of Alzheimer's memory deficit achieved by reducing 'excessive inhibition'
A new drug target to fight Alzheimer's disease has been discovered by a research team led by Gong Chen, a Professor of Biology and the Verne M. Willaman Chair in Life Sciences at Penn State...
View ArticleAnti-dsDNA, surface-expressed TLR4 and endosomal TLR9 cooperate to exacerbate...
The study by Lee et al reveals that risk factors, pathogenic anti-dsDNA and combined activation of extracellular and intracellular TLRs, induce SLE syndromes in normal mice. Hence, ongoing studies...
View ArticleThe analytical of PM2.5 in atmospheric fine particulate matter by GC/MS
Recently, the extraction of PAHs in particulates by temperature controlled ultrasonic extraction has been successfully applied to the determination of 24 kinds of PAHs in PM2.5, later we want to apply...
View ArticleDiabetes distress vs. depression: Are people with type 2 being misdiagnosed?
Researchers have long understood there is a strong association between diabetes and depression. But new research presented at the American Diabetes Association's 74th Scientific Sessions® shows that...
View ArticleStem cells in neurodegeneration: challenges and future neurotherapeutic...
Neurodegenerative disorders cause irreversible damage to the brain and affect an increasing number of people worldwide. Although promising, the use of neuronal stem cells requires a better...
View ArticleRapid identification of multiple bacteria on a microfluidic chip
We developed a microfluidic device to integrate sample introduction, bacteria culturing and results reading. The identification of multiple bacteria was achieved by combining the spatial resolution of...
View ArticleVariation in journal access pricing across institutions
Bundled journal access agreements between journal publishers and research institutions display variability in pricing that cannot be explained by institution characteristics alone, according to a...
View ArticleContinent-wide organic pollution in Europe’s freshwater systems
Organic chemicals such as pesticides and industrial chemicals may pose a continent-scale threat to freshwater ecosystems, according to a study. The threats posed by organic chemicals to freshwater...
View ArticleSocial spider behavior may influence division of labor
Spiders with different behavioral tendencies display different preferences and proficiencies for various tasks in a social colony, according to a study. Division of labor based on morphological or...
View ArticleViolent crime trials at London’s Old Bailey
Lexical trends in transcripts of London trials between 1760 and 1913 reveal a gradual decline in Western society's tolerance of violence, according to a study. To examine the evolution of the Western...
View ArticleReconstructing the population dynamics of passenger pigeons
Researchers have reconstructed the population dynamics of extinct passenger pigeons and found that dramatic natural changes in population may have rendered the birds vulnerable to human influences and...
View ArticleClimate and migration in pre-Columbian Peru
Genetic evidence from Peru identifies periods of migration in pre-Columbian Andean societies possibly linked to changes in local climates, according to a study. Archaeologists previously identified...
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